Research overview
The group conducts research on (resorbable) polymeric materials and structures for use in medical devices and in delivery of relevant biologically active compounds, (bio)artificial organs, cell-material interactions and tissue engineering. From our work on flexible resorbable materials, already one spin-off company has been created.
Current research topics include:
- Preparation of resorbable polymers for medical applications by ring opening polymerization and radical photo-polymerization
- Composite resorbable materials for fracture reconstruction in maxillofacial surgery.
- Development of designed advanced microstructures by stereolithography
- Engineering musculoskeletal and cardiovascular tissues in bioreactors using designed anisotropic scaffold architectures prepared from biologically active materials
- Membranes for artificial and (bio)artificial kidney devices and tissue eengineering scaffolds
- Membranes for bioseparations and membrane chromatography.
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Computer designed tissue engineering scaffold built by stereolithography using a degradable polymeric resin (A). MicroCT analysis shows that the built structure precisely matches the design (B). SEM images show the layer-by- layer nature of the building process (C). The scaffolds show excellent cell adhesion and proliferation (D). |
Mixed matrix membranes (MMM) for selective adsorption and removal of toxins from blood. In this concept, adsorptive particles are incorporated into a highly porous membrane combining filtration and adsorption in one ste |
