The group conducts research on (resorbable) polymeric materials and structures for use in medical devices and in delivery of relevant biologically active compounds, (bio)artificial organs, cell-material interactions and tissue engineering. From our work on flexible resorbable materials, already one spin-off company has been created.
Current research topics include:
- Preparation of resorbable polymers for medical applications by ring opening polymerization and radical photo-polymerization
- Composite resorbable materials for fracture reconstruction in maxillofacial surgery.
- Development of designed advanced microstructures by stereolithography
- Engineering musculoskeletal and cardiovascular tissues in bioreactors using designed anisotropic scaffold architectures prepared from biologically active materials
- Membranes for artificial and (bio)artificial kidney devices and tissue eengineering scaffolds
- Membranes for bioseparations and membrane chromatography.
Computer designed tissue engineering scaffold built by stereolithography using a degradable polymeric resin (A). MicroCT analysis shows that the built structure precisely matches the design (B). SEM images show the layer-by- layer nature of the building process (C). The scaffolds show excellent cell adhesion and proliferation (D).
Mixed matrix membranes (MMM) for selective adsorption and removal of toxins from blood. In this concept, adsorptive particles are incorporated into a highly porous membrane combining filtration and adsorption in one ste